Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505125 | 1.00 | HTR6 (0.56) | HTR6PPARGPPARDPPARAKDM4E | |
| SCHEMBL4023676 | 0.89 | KDM4E (0.51) | HTR6PPARGPPARDPPARAKDM4E | |
| SCHEMBL260867 | 0.86 | HTR6 (0.68) | HTR6L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL30644286 | 0.86 | HTR6 (0.68) | HTR6L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL30285388 | 0.85 | HTR6 (0.58) | HTR6PPARGPPARDPPARAKDM4E | |
| SCHEMBL3684432 | 0.85 | HTR6 (0.58) | HTR6PPARGPPARDPPARAKDM4E | |
| SCHEMBL11218072 | 0.82 | HTR6 (0.59) | HTR6KDM4EUBE2NL3MBTL1HTT | |
| SCHEMBL30949526 | 0.82 | HTR6 (0.59) | HTR6KDM4EUBE2NL3MBTL1HTT | |
| SCHEMBL10823230 | 0.82 | HTR6 (0.56) | HTR6KDM4EUBE2NL3MBTL1HTT | |
| SCHEMBL4560894 | 0.82 | HTR6 (0.56) | HTR6KDM4EUBE2NL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |