Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743140 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL20743137 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL30645011 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL20743093 | 0.82 | IRAK4 (0.53) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL30645121 | 0.82 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL20743189 | 0.82 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL30645027 | 0.82 | IRAK4 (0.53) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL20743990 | 0.81 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL20743761 | 0.81 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL20743099 | 0.81 | RAB9A (0.48) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | claimed |
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |