Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743189 | 1.00 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2HTTPKM | |
| SCHEMBL21821314 | 0.86 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2HTTPKM | |
| SCHEMBL20743093 | 0.84 | IRAK4 (0.53) | NPC1RAB9ASMN1; SMN2HTTPKM | |
| SCHEMBL30645027 | 0.84 | IRAK4 (0.53) | NPC1RAB9ASMN1; SMN2HTTPKM | |
| SCHEMBL20743761 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL30645019 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL20743099 | 0.83 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2HTTPKM | |
| SCHEMBL28429125 | 0.82 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL20743140 | 0.82 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL30645024 | 0.82 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |