Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | GPR4 | P46093 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210120 | 0.94 | CYP4F2 (0.50) | CYP4F2GPR119GPR4RXFP1DGAT1 | |
| SCHEMBL16111442 | 0.94 | CYP4F2 (0.50) | CYP4F2GPR119GPR4RXFP1DGAT1 | |
| SCHEMBL23649400 | 0.89 | HRH2 (0.50) | CYP4F2GPR119DGAT1EPHX2HRH2 | |
| SCHEMBL30433080 | 0.89 | HRH2 (0.50) | CYP4F2GPR119DGAT1EPHX2HRH2 | |
| SCHEMBL31210089 | 0.82 | LTA4H (0.46) | KDM4ETDP1 | |
| SCHEMBL26690765 | 0.82 | LTA4H (0.46) | KDM4ETDP1 | |
| SCHEMBL25399048 | 0.81 | CYP4F2 (0.50) | CYP4F2GPR119GPR4RXFP1EPHX2 | |
| SCHEMBL27380506 | 0.81 | GPR119 (0.48) | CYP4F2GPR119GPR4HRH2HRH1 | |
| SCHEMBL27380536 | 0.79 | GPR119 (0.49) | CYP4F2GPR119GPR4RXFP1EPHX2 | |
| SCHEMBL31212755 | 0.79 | GPR119 (0.50) | GPR119DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514782-A1 | AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | Astrazeneca AB (SE) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023222850-A1 | AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | ASTRAZENECA AB (SE) | 2023-11-23 | — | — | WO | disclosed |