Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.63 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.63 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653148 | 0.85 | ALDH1A1 (0.65) | ATMALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6653154 | 0.85 | ALDH1A1 (0.65) | ATMALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6645827 | 0.84 | ATM (0.52) | ATMLMNAPLIN1PLIN5ABHD5 | |
| SCHEMBL7624150 | 0.83 | ATM (0.55) | ATMLMNAPLIN1PLIN5ABHD5 | |
| SCHEMBL25764477 | 0.82 | ALDH1A1 (0.60) | ATMLMNAPLIN1PLIN5ABHD5 | |
| Tyrphostin Ag 494 SCHEMBL15362064 | 0.81 | KMT2A (0.74) | LMNAPLIN1PLIN5ABHD5MCL1 | |
| Tyrphostin Ag 494 SCHEMBL20645572 | 0.81 | KMT2A (0.74) | LMNAPLIN1PLIN5ABHD5MCL1 | |
| SCHEMBL3614719 | 0.81 | ALDH1A1 (0.75) | ATMLMNAPLIN1PLIN5ABHD5 | |
| SCHEMBL3614715 | 0.81 | ALDH1A1 (0.75) | ATMLMNAPLIN1PLIN5ABHD5 | |
| SCHEMBL6344579 | 0.80 | MCL1 (0.68) | ATMLMNAPLIN1PLIN5ABHD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |