Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.65 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653154 | 1.00 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL30645352 | 0.85 | ATM (0.70) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL801207 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL13400584 | 0.81 | MEN1 (0.68) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL782201 | 0.80 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL13376833 | 0.80 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL782202 | 0.80 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL13060204 | 0.80 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDCISD1KDM4E | |
| SCHEMBL5950161 | 0.79 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAPK1BLM | |
| SCHEMBL5950156 | 0.79 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAPK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1431280-A1 | ARYL SULFAMATE DERIVATIVES | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | SULT1A1, STS, CYP26A1 | ALDH1A1 1187/4885CYP3A4 208/4885HPGD 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.