Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645388 | 0.86 | CRBN (0.31) | PTPN1 | |
| SCHEMBL29406154 | 0.83 | APP (0.37) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL13663953 | 0.81 | APP (0.36) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL13746651 | 0.81 | APP (0.35) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL29406722 | 0.80 | APP (0.35) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL15744228 | 0.80 | APP (0.35) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL22863326 | 0.80 | APP (0.35) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL9880208 | 0.80 | APP (0.35) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL13667312 | 0.80 | APP (0.36) | APPALOX5PTPN1NR1H4BACE1 | |
| SCHEMBL23941477 | 0.79 | ALOX5 (0.37) | APPALOX5PTPN1NR1H4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116687920-A | Application of marine bisindole compound combined with cytarabine (Ara-C) in preparation of drugs for treating Acute Myeloid Leukemia (AML) | 上海海洋大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116687920-A | Application of marine bisindole compound combined with cytarabine (Ara-C) in preparation of drugs for treating Acute Myeloid Leukemia (AML) | 上海海洋大学 | 2023-09-05 | — | — | CN | disclosed |