Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406722 | 1.00 | APP (0.35) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL9880208 | 1.00 | APP (0.35) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL22863326 | 1.00 | APP (0.35) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL13746651 | 0.94 | APP (0.35) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL23941477 | 0.92 | ALOX5 (0.37) | APPALOX5NR1H4BACE1PTPN1 | |
| SCHEMBL22863355 | 0.92 | ALOX5 (0.37) | APPALOX5NR1H4BACE1PTPN1 | |
| SCHEMBL13663953 | 0.91 | APP (0.36) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL29406154 | 0.90 | APP (0.37) | APPALOX5NR1H4ABCG2BACE1 | |
| SCHEMBL21538194 | 0.90 | ALOX5 (0.36) | APPALOX5NR1H4BACE1PTPN1 | |
| SCHEMBL22863234 | 0.90 | ALOX5 (0.36) | APPALOX5NR1H4BACE1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452679-B1 | TRIPRENYLPHENOLIC CYTOPROTECTIVE AGENT | UNIV TOKYO NAT UNIV CORP (JP) | 2014-05-28 | — | — | EP | disclosed |