Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 13/20 | 1.00 |
| ▸ | TNFSF11 | O14788 | 11/20 | 1.00 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29477172 | 1.00 | TNF (1.00) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL1270919 | 1.00 | TNF (1.00) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL15159836 | 0.90 | TNF (0.81) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL21162208 | 0.89 | TNF (0.80) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL15158389 | 0.89 | TNF (0.79) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL15832294 | 0.89 | TNF (0.79) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL15832298 | 0.88 | TNF (0.78) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL15159837 | 0.87 | TNF (0.76) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL20975834 | 0.85 | TNF (0.74) | TNFTNFSF11TNFRSF1A | |
| SCHEMBL19654771 | 0.85 | TNF (0.74) | TNFTNFSF11TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230414560-A1 | COMPOSITIONS AND METHODS FOR TREATING ECZEMA | General Nutraceutical Technology LLC | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414560-A1 | COMPOSITIONS AND METHODS FOR TREATING ECZEMA | ELANE, TSLP, EPX | TNF 523/4885TNFSF11 4116/4885TNFRSF1A 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.