Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 10/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111051 | 1.00 | ACHE (0.50) | ACHEBACE1ABCG2KDRBRAF | |
| SCHEMBL29111060 | 0.86 | PDGFRA (0.62) | KDRPDGFRAKITPDGFRB | |
| SCHEMBL30646026 | 0.86 | PDGFRA (0.62) | KDRPDGFRAKITPDGFRB | |
| SCHEMBL29111054 | 0.85 | ACHE (0.51) | ACHEBACE1ABCG2KDRBRAF | |
| SCHEMBL30646030 | 0.85 | ACHE (0.51) | ACHEBACE1ABCG2KDRBRAF | |
| SCHEMBL29111048 | 0.82 | BRAF (0.55) | ACHEBACE1KDRBRAFPDGFRA | |
| SCHEMBL664198 | 0.79 | KDR (0.48) | KDRBRAFPDGFRAKITCSF1R | |
| SCHEMBL664801 | 0.79 | KDR (0.48) | KDRBRAFPDGFRAKITCSF1R | |
| SCHEMBL29111056 | 0.76 | KDR (0.45) | ACHEBACE1KDRPDGFRAFLT3 | |
| SCHEMBL30646069 | 0.76 | KDR (0.45) | ACHEBACE1KDRPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |