Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 8/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111054 | 1.00 | ACHE (0.51) | ACHEBACE1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29111048 | 0.90 | BRAF (0.55) | ACHEBACE1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29111053 | 0.87 | PDGFRA (0.62) | PDGFRAKITPDGFRBKDR | |
| SCHEMBL30646019 | 0.87 | PDGFRA (0.62) | PDGFRAKITPDGFRBKDR | |
| SCHEMBL28421305 | 0.86 | PIK3CD (0.54) | ACHEBACE1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29111051 | 0.85 | ACHE (0.50) | ACHEBACE1PDGFRAKITPDGFRB | |
| SCHEMBL30646045 | 0.85 | ACHE (0.50) | ACHEBACE1PDGFRAKITPDGFRB | |
| SCHEMBL28433303 | 0.83 | KDR (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGPDGFRA | |
| SCHEMBL30646043 | 0.83 | KDR (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGPDGFRA | |
| SCHEMBL28425382 | 0.79 | PDGFRA (0.44) | ACHEBACE1PDGFRAKITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |