Podocarpusflavone A

Podocarpusflavone A

SCHEMBL29496316

COc1ccc(-c2cc(=O)c3c(O)cc(O)c(-c4cc(-c5cc(=O)c6c(O)cc(O)cc6o5)ccc4O)c3o2)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.72
▸ KMT2A Q03164 4/20 0.72
▸ MAPT P10636 3/20 0.72
▸ USP2 O75604 2/20 0.72
▸ TP53 P04637 2/20 0.72
▸ TDP1 Q9NUW8 2/20 0.72
▸ MAOB P27338 2/20 0.72
▸ ALDH1A1 P00352 2/20 0.72
▸ CYP1A1 P04798 2/20 0.72
▸ CYP1A2 P05177 2/20 0.72
▸ CYP1B1 Q16678 2/20 0.72
▸ FLT3 P36888 2/20 0.72
▸ IP6K2 Q9UHH9 2/20 0.72
▸ NPC1 O15118 1/20 0.72
▸ LMNA P02545 1/20 0.72
▸ CYP3A4 P08684 1/20 0.72
▸ CYP2D6 P10635 1/20 0.72
▸ CYP2C9 P11712 1/20 0.72
▸ KCNE1 P15382 1/20 0.72
▸ MAOA P21397 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Podocarpusflavone A SCHEMBL25937932 1.00 MEN1 (0.72) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone B SCHEMBL29496271 0.96 MAPT (0.73) MEN1KMT2AMAPTUSP2TP53
Podocarpusflavone B SCHEMBL27350627 0.96 MAPT (0.73) MEN1KMT2AMAPTUSP2TP53
7'',4'''-Dimethylamentoflavone SCHEMBL30646161 0.92 APP (0.72) MEN1KMT2AMAPTUSP2TP53
Isoginkgetin SCHEMBL22459983 0.92 MEN1 (0.80) MEN1KMT2AMAPTUSP2TP53
Isoginkgetin SCHEMBL30293900 0.92 MEN1 (0.80) MEN1KMT2AMAPTUSP2TP53
7'',4'''-Dimethylamentoflavone SCHEMBL27350631 0.92 APP (0.72) MEN1KMT2AMAPTUSP2TP53
Sequoiaflavone SCHEMBL1158361 0.92 MEN1 (0.73) MEN1KMT2AMAPTUSP2TP53
Sequoiaflavone SCHEMBL30646160 0.92 MEN1 (0.73) MEN1KMT2AMAPTUSP2TP53
Amentoflavone SCHEMBL312563 0.90 MEN1 (0.80) MEN1KMT2AMAPTUSP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687999-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS OBI Pharma, Inc. (TW) 2026-02-11 — — EP claimed
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 — — WO claimed
WO-2024206480-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS O B I PHARMA, INC. (TW) 2024-10-03 — — WO claimed
EP-4687999-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS OBI Pharma, Inc. (TW) 2026-02-11 — — EP disclosed
EP-4615990-A1 GLYCOSYNTHASE VARIANTS FOR ANTIBODY-DRUG CONJUGATE ENGINEERING OBI Pharma, Inc. (TW) 2025-09-17 — — EP disclosed
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2025-07-17 — — US disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 — — US disclosed
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 — — WO disclosed
WO-2024206480-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS O B I PHARMA, INC. (TW) 2024-10-03 — — WO disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
WO-2024102523-A1 GLYCOSYNTHASE VARIANTS FOR ANTIBODY-DRUG CONJUGATE ENGINEERING OBI PHARMA, INC. (TW) 2024-05-16 — — WO disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 — — WO disclosed
US-20230233514-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING, INC. 2023-07-27 — — US disclosed
EP-3498297-B1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM STALICLA S A (CH) 2023-06-21 — — EP disclosed
EP-4167984-A1 ANTI-VIRAL COMPOUNDS AND METHODS OF USING SAME Flagship Pioneering, Inc. (US) 2023-04-26 — — EP disclosed
WO-2023037254-A1 METHODS AND COMPOUNDS FOR TREATING CORONAVIRIDAE VIRUS INFECTIONS DIDENKO KIRILL (MX) 2023-03-16 — — WO disclosed
US-20220288404-A1 METHODS FOR APPLYING TUMOR TREATING FIELDS IN COMBINATION WITH CANCER TREATING THERAPEUTICS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-09-15 — — US disclosed
WO-2022192719-A2 METHODS FOR APPLYING TUMOR TREATING FIELDS IN COMBINATION WITH CANCER TREATING THERAPEUTICS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-09-15 — — WO disclosed
US-11439627-B2 Pharmaceutical composition for the treatment of autism Stalicla S.A. (CH) 2022-09-13 — — US disclosed
EP-3984555-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM Stalicla S.A. (CH) 2022-04-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233514-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME ACE2, ACE, EIF2AK2 MEN1 4255/4885KMT2A 2967/4885MAPT 3743/4885
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, MAVS MEN1 3073/4885KMT2A 3798/4885MAPT 1798/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 MEN1 732/4885KMT2A 2058/4885MAPT 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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