Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31266682 | 0.74 | POLB (0.64) | KDM4EALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL30647640 | 0.74 | POLB (0.64) | KDM4EALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL2372875 | 0.71 | NCOA1 (0.50) | NCOA1NCOA3PLA2G10KDM4EALDH1A1 | |
| SCHEMBL19691115 | 0.70 | PLA2G10 (0.61) | NCOA1NCOA3PLA2G10KDM4EALOX15 | |
| SCHEMBL7719697 | 0.68 | L3MBTL1 (0.63) | NCOA1NCOA3KDM4EALDH1A1NPC1 | |
| SCHEMBL31214767 | 0.68 | NCOA1 (0.59) | NCOA1NCOA3KDM4EPOLBGRM2 | |
| Hydrochloric Acid SCHEMBL28252270 | 0.67 | L3MBTL1 (0.61) | NCOA1NCOA3KDM4EALDH1A1NPC1 | |
| SCHEMBL28691005 | 0.66 | NCOA1 (0.60) | NCOA1NCOA3KDM4EPOLBGRM2 | |
| SCHEMBL9574610 | 0.66 | NCOA1 (0.60) | NCOA1NCOA3GRM2 | |
| SCHEMBL5202032 | 0.66 | NCOA1 (0.65) | NCOA1NCOA3KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543878-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | Astrazeneca AB (SE) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247489-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2023-12-28 | — | — | WO | disclosed |