Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848521 | 0.75 | CYP1A2 (0.51) | KDM4EPOLBRXFP1LMNASMN1; SMN2 | |
| SCHEMBL2386140 | 0.73 | MEN1 (0.44) | NCOA1NCOA3TACR3KDM4EPOLB | |
| SCHEMBL28691005 | 0.72 | NCOA1 (0.60) | NCOA1NCOA3IKBKBKDM4EPOLB | |
| SCHEMBL9574610 | 0.72 | NCOA1 (0.60) | NCOA1NCOA3GRM2 | |
| SCHEMBL5202032 | 0.72 | NCOA1 (0.65) | NCOA1NCOA3IKBKBKDM4EPOLB | |
| SCHEMBL7719697 | 0.71 | L3MBTL1 (0.63) | NCOA1NCOA3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL31214767 | 0.71 | NCOA1 (0.59) | NCOA1NCOA3IKBKBKDM4EPOLB | |
| SCHEMBL6457986 | 0.71 | KDM4E (0.65) | NCOA1NCOA3KDM4EPOLBHTT | |
| SCHEMBL30647680 | 0.71 | NCOA1 (0.43) | NCOA1NCOA3KDM4EPOLBLMNA | |
| SCHEMBL379807 | 0.70 | LMNA (0.76) | NCOA1NCOA3TACR3KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |