SCHEMBL30648461

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	2/20	0.46

▸	BACE1	P56817	10/20	0.42

▸	BACE2	Q9Y5Z0	3/20	0.42

▸	ENPEP	Q07075	5/20	0.39

▸	TASP1	Q9H6P5	1/20	0.39

▸	CTSD	P07339	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29710468	0.89	BACE1 (0.45)	MMEBACE1CTSD
SCHEMBL29777830	0.87	MME (0.46)	MME
SCHEMBL29783651	0.87	BACE1 (0.42)	BACE1BACE2ENPEPCTSD
SCHEMBL29444702	0.86	ENPEP (0.51)	MMEBACE1ENPEPTASP1
SCHEMBL30123134	0.86	BACE1 (0.45)	BACE1BACE2CTSD
SCHEMBL29783650	0.86	ENPEP (0.41)	MMEBACE1ENPEP
SCHEMBL8656318	0.86	ALDH1A1 (0.45)	MMEBACE1CTSD
SCHEMBL8656320	0.86	ALDH1A1 (0.45)	MMEBACE1CTSD
SCHEMBL29444705	0.85	ENPEP (0.52)	MMEBACE1ENPEPTASP1
SCHEMBL29874434	0.84	MME (0.51)	MMEBACE1TASP1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116948034-B	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2024-06-25	—	—	CN	disclosed
CN-116948034-A	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2023-10-27	—	—	CN	disclosed