SCHEMBL30726588

CC(C)[C@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.64

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	9/20	0.63

▸	CCKBR	P32239	4/20	0.63

▸	C5AR1	P21730	2/20	0.63

▸	NMBR	P28336	2/20	0.62

▸	GRPR	P30550	2/20	0.62

▸	GCGR	P47871	3/20	0.59

▸	CALCR	P30988	4/20	0.58

▸	NPY1R	P25929	1/20	0.58

▸	NPY2R	P49146	1/20	0.58

▸	NPY4R	P50391	1/20	0.58

▸	NPY5R	Q15761	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30432529	0.90	C5AR1 (0.67)	GLP1RCCKBRC5AR1NMBRGRPR
SCHEMBL31000951	0.90	C5AR1 (0.71)	GLP1RCCKBRC5AR1NMBRGRPR
SCHEMBL30537029	0.89	GLP1R (0.72)	GLP1RCCKBRC5AR1CALCRNPY1R
SCHEMBL30436196	0.89	NPY1R (0.67)	GLP1RCCKBRC5AR1GCGRCALCR
SCHEMBL31000923	0.89	GLP1R (0.68)	GLP1RCCKBRNMBRGRPRCALCR
SCHEMBL30648477	0.89	GLP1R (0.67)	GLP1RCCKBRC5AR1NMBRGRPR
SCHEMBL31000945	0.88	C5AR1 (0.73)	GLP1RCCKBRC5AR1GCGRNPY1R
SCHEMBL31105353	0.88	GLP1R (0.70)	GLP1RCCKBRC5AR1CALCRNPY1R
SCHEMBL29945131	0.87	NMBR (0.62)	GLP1RCCKBRC5AR1NMBRGRPR
SCHEMBL31105456	0.87	NPY2R (0.71)	GLP1RC5AR1GCGRNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed