Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16533052 | 0.96 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL26639888 | 0.93 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16545198 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNAP2RX7 | |
| SCHEMBL19940203 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16533682 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ALMNAP2RX7 | |
| SCHEMBL16533499 | 0.84 | MEN1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31412386 | 0.84 | MEN1 (0.43) | SMN1; SMN2MEN1KMT2ALMNAP2RX7 | |
| SCHEMBL31412426 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ALMNAP2RX7 | |
| SCHEMBL31247417 | 0.84 | P2RX7 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31412398 | 0.83 | MEN1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522604-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220225-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | WO | disclosed |