Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 7/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | RORA | P35398 | 3/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | OSBP | P22059 | 1/20 | 0.34 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30653161 | 0.67 | PLA2G1B (0.55) | NPC1L1PLA2G1BMEN1KMT2AUSP2 | |
| SCHEMBL16152196 | 0.67 | PLA2G1B (0.55) | NPC1L1PLA2G1BMEN1KMT2AUSP2 | |
| SCHEMBL8408231 | 0.67 | PLA2G1B (0.55) | NPC1L1PLA2G1BMEN1KMT2AUSP2 | |
| SCHEMBL18199154 | 0.66 | EBP (0.52) | EBPNPC1L1PLA2G1BMEN1KMT2A | |
| SCHEMBL17487215 | 0.66 | EBP (0.55) | EBPNPC1L1PLA2G1BMEN1KMT2A | |
| SCHEMBL18714858 | 0.66 | EBP (0.55) | EBPNPC1L1PLA2G1BMEN1KMT2A | |
| SCHEMBL18714859 | 0.66 | EBP (0.55) | EBPNPC1L1PLA2G1BMEN1KMT2A | |
| SCHEMBL17487216 | 0.66 | EBP (0.55) | EBPNPC1L1PLA2G1BMEN1KMT2A | |
| SCHEMBL14129628 | 0.63 | RORC (0.46) | EBPNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL13185816 | 0.60 | EBP (0.55) | EBPNPC1L1PLA2G1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |