Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588200 | 0.82 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27539162 | 0.82 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27606029 | 0.82 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27756696 | 0.81 | TLR8 (0.32) | PDXK | |
| SCHEMBL27550757 | 0.80 | PDXK (0.40) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28558604 | 0.79 | PDXK (0.49) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28922439 | 0.77 | KDM4E (0.50) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Palmitic Acid SCHEMBL29361257 | 0.74 | ALDH1A1 (0.63) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Decanoic Acid SCHEMBL30694319 | 0.74 | ALDH1A1 (0.63) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28806636 | 0.74 | KDM4E (0.44) | PDXKKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648362-A2 | FILM COMPRISING THERAPEUTIC AGENTS | Maibach, Todd (US) | 2006-04-26 | — | — | EP | claimed |
| WO-2005004989-A2 | FILM COMPRISING THERAPEUTIC AGENTS | MAIBACH TODD (US) | 2005-01-20 | — | — | WO | claimed |
| CN-103945830-B | Protein-conjugated polymer micelle | 南达科他州立大学 | 2017-06-06 | — | — | CN | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |