Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661129 | 1.00 | EDNRA (0.51) | EDNRAL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL2470943 | 0.82 | EDNRA (0.51) | EDNRAL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL26661130 | 0.81 | EDNRA (0.53) | EDNRAL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL31351336 | 0.81 | EDNRA (0.53) | EDNRAL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL31351339 | 0.79 | L3MBTL1 (0.46) | L3MBTL1TDP1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL26661109 | 0.79 | L3MBTL1 (0.46) | L3MBTL1TDP1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL15465845 | 0.78 | EDNRA (0.59) | EDNRANPC1RAB9ACASP3SENP8 | |
| SCHEMBL31351338 | 0.76 | EDNRA (0.60) | EDNRAL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL26661119 | 0.76 | EDNRA (0.60) | EDNRAL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL31351335 | 0.75 | GABRA1 (0.55) | EDNRAL3MBTL1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532013-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-04-09 | — | — | EP | disclosed |
| CN-119421879-A | Novel derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-02-11 | — | — | CN | disclosed |
| WO-2023227697-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |