Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16636878 | 1.00 | NT5E (0.36) | NT5EAHRMAPTCSNK2A1LMNA | |
| SCHEMBL28495362 | 0.82 | NT5E (0.37) | NT5EMAPTLMNA | |
| SCHEMBL26998825 | 0.82 | ACHE (0.40) | NT5EAHRMAPTLMNAKDM4E | |
| SCHEMBL28499601 | 0.78 | AXL (0.38) | MAPT | |
| SCHEMBL7699263 | 0.73 | NT5E (0.46) | NT5ECYP2C19 | |
| SCHEMBL4015829 | 0.73 | NT5E (0.64) | NT5EMAPTLMNAKDM4ECYP3A4 | |
| SCHEMBL31218411 | 0.73 | NT5E (0.64) | NT5EMAPTLMNAKDM4ECYP3A4 | |
| SCHEMBL29531805 | 0.73 | NT5E (0.46) | NT5ECYP2C19 | |
| SCHEMBL22029026 | 0.73 | HTT (0.37) | AHRCSNK2A1 | |
| SCHEMBL17748330 | 0.73 | DHODH (0.38) | MAPTKDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486734-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-119137112-A | Quinoline cGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |