Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656216 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KMT2ARXFP1MEN1NPC1 | |
| SCHEMBL30656285 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KMT2ARXFP1MEN1NPC1 | |
| SCHEMBL30656049 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2ARXFP1MEN1NPC1 | |
| SCHEMBL30656237 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ARXFP1MEN1NPC1 | |
| SCHEMBL30852546 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ARXFP1HPGDKDM4E | |
| SCHEMBL21561035 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KMT2ARXFP1MEN1HPGD | |
| SCHEMBL25598894 | 0.77 | IKBKB (0.56) | ALDH1A1KMT2ARXFP1HPGDKDM4E | |
| SCHEMBL14923786 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ARXFP1HPGDKDM4E | |
| SCHEMBL19051440 | 0.75 | RXFP1 (0.65) | ALDH1A1KMT2ARXFP1MEN1NPC1 | |
| SCHEMBL1461650 | 0.74 | PIK3CA (0.54) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | claimed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | claimed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |