Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 9/20 | 0.49 |
| ▸ | CASP7 | P55210 | 9/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656216 | 0.97 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30656049 | 0.95 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30656153 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30656237 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27883168 | 0.74 | KDM4E (0.57) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23168043 | 0.71 | CNR2 (0.50) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30152422 | 0.71 | CNR2 (0.50) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL21561114 | 0.70 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL22279004 | 0.70 | CNR2 (0.52) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11015453 | 0.69 | CASP1 (0.49) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |