SCHEMBL30656198

SCHEMBL30656198

Cc1sc2ccc(OCc3cccnc3O)cc2c1C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.33
CD274 Q9NZQ7 7/20 0.33
PDCD1 Q15116 4/20 0.33
EDNRA P25101 1/20 0.33
SLC26A4 O43511 1/20 0.32
PPARG P37231 1/20 0.31
HPGDS O60760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26792926 1.00 SCN9A (0.33) SCN9ACD274PDCD1EDNRASLC26A4
SCHEMBL30656325 1.00 SCN9A (0.33) SCN9ACD274PDCD1EDNRASLC26A4
SCHEMBL26793645 0.90 CD274 (0.34) CD274EDNRA
SCHEMBL30656105 0.90 CD274 (0.34) CD274EDNRA
SCHEMBL30656189 0.90 SCN9A (0.36) SCN9AEDNRASLC26A4HPGDS
SCHEMBL30656016 0.88 CD38 (0.36) SCN9ACD274PDCD1EDNRA
SCHEMBL30656176 0.88 CD38 (0.36) SCN9ACD274PDCD1EDNRA
SCHEMBL30656047 0.86 GPR132 (0.43) PPARG
SCHEMBL30656154 0.86 SCN9A (0.44) SCN9A
SCHEMBL30655999 0.86 GPR132 (0.43) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed