SCHEMBL30656189

SCHEMBL30656189

Cc1sc2ccc(OCc3cccnc3O)cc2c1C(=O)N[C@@H](C)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.36
MAOB P27338 5/20 0.35
EDNRA P25101 1/20 0.35
HPGDS O60760 2/20 0.34
GPR132 Q9UNW8 1/20 0.34
SCN3A Q9NY46 1/20 0.34
MAOA P21397 2/20 0.33
LIMK1 P53667 1/20 0.33
SLC26A4 O43511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656180 0.90 HPGDS (0.37) SCN9AMAOBEDNRAHPGDSGPR132
SCHEMBL30656124 0.90 HPGDS (0.37) SCN9AMAOBEDNRAHPGDSGPR132
SCHEMBL26792926 0.90 SCN9A (0.33) SCN9AEDNRAHPGDSSLC26A4
SCHEMBL30656325 0.90 SCN9A (0.33) SCN9AEDNRAHPGDSSLC26A4
SCHEMBL30656198 0.90 SCN9A (0.33) SCN9AEDNRAHPGDSSLC26A4
SCHEMBL30656258 0.88 CD38 (0.37) SCN9AMAOBEDNRAHPGDSGPR132
SCHEMBL30656226 0.88 CD38 (0.37) SCN9AMAOBEDNRAHPGDSGPR132
SCHEMBL31350322 0.86 EDNRA (0.38) MAOBEDNRASLC26A4
SCHEMBL30656142 0.85 PARP10 (0.43) MAOBEDNRAGPR132MAOA
SCHEMBL30656003 0.85 SCN9A (0.52) SCN9AMAOBSCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed