SCHEMBL30656275

SCHEMBL30656275

CNC(=O)c1c(C(F)F)sc2ccc(OCc3ccccc3)cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 1/20 0.52
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.42
MAOB P27338 3/20 0.41
MAOA P21397 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMPD1 P17405 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26661130 0.88 EDNRA (0.53) EDNRACASP3SENP8SENP7SENP6
SCHEMBL31351336 0.88 EDNRA (0.53) EDNRACASP3SENP8SENP7SENP6
SCHEMBL26661120 0.88 EDNRA (0.56) EDNRAMEN1KMT2ACASP3SENP8
SCHEMBL30656301 0.86 EDNRA (0.47) EDNRAMEN1KMT2ACASP3SENP8
SCHEMBL30656349 0.85 ALOX5 (0.52) EDNRAMEN1KMT2AMAOBKDM4E
SCHEMBL30656021 0.84 EDNRA (0.53) EDNRAMEN1KMT2ACASP3SENP8
SCHEMBL30656217 0.83 EDNRA (0.46) EDNRAMAOBMAOAKDM4EMAPT
SCHEMBL30656023 0.82 EDNRA (0.44) EDNRAMEN1KMT2AKDM4EMAPT
SCHEMBL30656268 0.82 SLC6A5 (0.49) EDNRAKMT2AMAOBMAOAMAPT
SCHEMBL30655991 0.82 SLC6A5 (0.51) EDNRAMEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed