SCHEMBL30656320

SCHEMBL30656320

Cc1sc2ccc(OCc3ccccc3)cc2c1C(=O)NC1CCN(C)C1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 11/20 0.49
HTR3A P46098 2/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
EDNRA P25101 1/20 0.43
MCHR1 Q99705 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
BTK Q06187 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26793496 0.95 SLC6A5 (0.49) SLC6A5HTR3AMAOAMAOBEDNRA
SCHEMBL30656061 0.88 SLC6A5 (0.47) SLC6A5HTR3AMAOAMAOBEDNRA
SCHEMBL30656281 0.84 SLC6A5 (0.39) SLC6A5BTK
SCHEMBL30656319 0.83 BRD4 (0.44) HTR3AMAOAMAOBEDNRAKDM4E
SCHEMBL30656073 0.83 EDNRA (0.47) HTR3AMAOAMAOBEDNRAKDM4E
SCHEMBL30656268 0.82 SLC6A5 (0.49) SLC6A5HTR3AMAOAMAOBEDNRA
SCHEMBL30656337 0.82 SSTR4 (0.42) SLC6A5BTK
SCHEMBL24470766 0.82 CASP3 (0.60) SLC6A5MAOAMAOBKDM4EMEN1
SCHEMBL24470564 0.82 CASP3 (0.60) SLC6A5MAOAMAOBKDM4EMEN1
SCHEMBL24470568 0.82 CASP3 (0.60) SLC6A5MAOAMAOBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed