Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656146 | 0.80 | KDM4E (0.52) | GAAHTTKDM4EALDH1A1LMNA | |
| SCHEMBL31524204 | 0.73 | CSNK1A1 (0.47) | GAAHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27883168 | 0.72 | KDM4E (0.57) | GAAHTTKDM4EALDH1A1LMNA | |
| SCHEMBL30656079 | 0.70 | KDM4E (0.47) | GAAHTTKDM4EALDH1A1LMNA | |
| SCHEMBL7283859 | 0.69 | PDE3B (0.44) | GAAHTTKDM4EALDH1A1LMNA | |
| SCHEMBL30656058 | 0.68 | ADORA1 (0.46) | GAAHTTKDM4EALDH1A1LMNA | |
| SCHEMBL30656353 | 0.68 | CCNA2 (0.63) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12449940 | 0.67 | GAA (0.40) | GAAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13567348 | 0.66 | GAA (0.39) | GAAHTTKDM4ESLC29A1 | |
| SCHEMBL26633002 | 0.66 | ADORA1 (0.50) | HTTKDM4EALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |