Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656347 | 0.80 | GAA (0.48) | KDM4EALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL30656079 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL27883168 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL12842048 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MAPK1L3MBTL1 | |
| SCHEMBL15831842 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL810713 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10LMNAHTT | |
| SCHEMBL9377841 | 0.69 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL30656367 | 0.69 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL4764036 | 0.68 | CSNK1A1 (0.50) | KDM4EALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL9640682 | 0.67 | TSHR (0.57) | KDM4EALDH1A1HSD17B10TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |