Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CLK1 | P49759 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661116 | 1.00 | LMNA (0.47) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL26661107 | 0.85 | LMNA (0.63) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL31351348 | 0.85 | LMNA (0.63) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL30656383 | 0.83 | LMNA (0.52) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL26661127 | 0.83 | LMNA (0.52) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL26661110 | 0.78 | LMNA (0.52) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL10958206 | 0.74 | PFKFB3 (0.54) | LMNAMAPK1L3MBTL1ATMTDP1 | |
| SCHEMBL20563093 | 0.74 | MAPT (0.48) | LMNAMAPK1L3MBTL1ATMTDP1 | |
| SCHEMBL30656385 | 0.74 | L3MBTL1 (0.44) | LMNAMAPK1L3MBTL1ATMTLR9 | |
| SCHEMBL26661118 | 0.74 | L3MBTL1 (0.44) | LMNAMAPK1L3MBTL1ATMTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532013-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-04-09 | — | — | EP | disclosed |
| CN-119421879-A | Novel derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-02-11 | — | — | CN | disclosed |
| WO-2023227697-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |