Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SCD | O00767 | 3/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257479 | 1.00 | OPRM1 (0.64) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL10169421 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3144674 | 0.82 | DRD2 (0.70) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL30102638 | 0.82 | DRD2 (0.70) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL29423860 | 0.81 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL367111 | 0.81 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3357163 | 0.80 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3353652 | 0.80 | PRKCI (0.44) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL30271235 | 0.80 | PRKCI (0.44) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL20212843 | 0.79 | OPRL1 (1.00) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217201-A2 | NOVEL PYRIMIDO-HETEROCYCLIC NOVEL COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATION THEREOF | 杭州德睿智药科技有限公司 | 2023-11-16 | — | — | WO | disclosed |