Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680097 | 1.00 | HTR2A (0.63) | HTR2AHTR2CMAOADRD2TSHR | |
| SCHEMBL4021920 | 1.00 | HTR2A (0.63) | HTR2AHTR2CMAOADRD2TSHR | |
| SCHEMBL1010752 | 1.00 | HTR2A (0.63) | HTR2AHTR2CMAOADRD2TSHR | |
| Hydrochloric Acid SCHEMBL30656686 | 0.98 | HTR2A (0.61) | HTR2AHTR2CMAOADRD2TSHR | |
| Hydrochloric Acid SCHEMBL29429458 | 0.98 | HTR2A (0.61) | HTR2AHTR2CMAOADRD2TSHR | |
| Hydrochloric Acid SCHEMBL28424341 | 0.98 | HTR2A (0.61) | HTR2AHTR2CMAOADRD2TSHR | |
| Hydrochloric Acid SCHEMBL29429462 | 0.98 | HTR2A (0.61) | HTR2AHTR2CMAOADRD2TSHR | |
| SCHEMBL22680298 | 0.86 | MAOA (0.54) | HTR2AHTR2CMAOADRD2TSHR | |
| SCHEMBL22680299 | 0.86 | MAOA (0.54) | HTR2AHTR2CMAOADRD2TSHR | |
| SCHEMBL626535 | 0.86 | MAOA (0.54) | HTR2AHTR2CMAOADRD2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417635-B | Pyrazolopyrimidines with anti-Respiratory Syncytial Virus (RSV) activity | 爱尔兰詹森科学公司 | 2024-01-02 | — | — | CN | disclosed |