Sugi Predict

Sugi Predict / Compounds / SCHEMBL626535

SCHEMBL626535

SCHEMBL626535

CC1NCCc2cc(F)ccc21

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 8/20 0.54
▸ DRD2 P14416 2/20 0.54
▸ TSHR P16473 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ DRD3 P35462 1/20 0.54
▸ HIF1A Q16665 1/20 0.54
▸ DRD4 P21917 1/20 0.54
▸ HTR2A P28223 1/20 0.50
▸ HTR2C P28335 1/20 0.50
▸ CYP2D6 P10635 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ PRCP P42785 1/20 0.42
▸ KDM4C Q9H3R0 1/20 0.41
▸ SRD5A1 P18405 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22680299 1.00 MAOA (0.54) MAOADRD2TSHRHSD17B10KDM4E
SCHEMBL22680298 1.00 MAOA (0.54) MAOADRD2TSHRHSD17B10KDM4E
SCHEMBL22680097 0.86 HTR2A (0.63) MAOADRD2TSHRHSD17B10KDM4E
SCHEMBL4021920 0.86 HTR2A (0.63) MAOADRD2TSHRHSD17B10KDM4E
SCHEMBL30656744 0.86 HTR2A (0.63) MAOADRD2TSHRHSD17B10KDM4E
SCHEMBL1010752 0.86 HTR2A (0.63) MAOADRD2TSHRHSD17B10KDM4E
Hydrochloric Acid SCHEMBL30656686 0.84 HTR2A (0.61) MAOADRD2TSHRHSD17B10KDM4E
Hydrochloric Acid SCHEMBL28424341 0.84 HTR2A (0.61) MAOADRD2TSHRHSD17B10KDM4E
Hydrochloric Acid SCHEMBL29429462 0.84 HTR2A (0.61) MAOADRD2TSHRHSD17B10KDM4E
Hydrochloric Acid SCHEMBL29429458 0.84 HTR2A (0.61) MAOADRD2TSHRHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784403-B1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2013-07-17 — — EP claimed
EP-1805177-B9 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2010-09-15 — — EP claimed
EP-1805177-B1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2010-04-28 — — EP claimed
US-7642269-B2 Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof YUHAN CORPORATION (KR) 2010-01-05 — — US claimed
EP-1805177-A4 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-07-29 — — EP claimed
US-7541366-B2 Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof YUHAN CORPORATION (KR) 2009-06-02 — — US claimed
US-20070249658-A1 Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof YUHAN CORPORATION (KR) 2007-10-25 — — US claimed
US-20070213358-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2007-09-13 — — US claimed
EP-1805177-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-07-11 — — EP claimed
EP-1784403-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 — — EP claimed
WO-2006038773-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-04-13 — — WO claimed
WO-2006025715-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 — — WO claimed
US-20240246965-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE EQUINORM LTD 2024-07-25 — — US disclosed
EP-4313985-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE Equinorm Ltd (FI) 2024-02-07 — — EP disclosed
CN-117412975-A Heterocyclic compounds and their use 伊科诺姆有限公司 2024-01-16 — — CN disclosed
CN-111417635-B Pyrazolopyrimidines with anti-Respiratory Syncytial Virus (RSV) activity 爱尔兰詹森科学公司 2024-01-02 — — CN disclosed
EP-1131312-B1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP LTD (KR) 2005-10-26 — — EP disclosed
US-6545008-B1 Inhibitory activity against gastric acid secretion YUHAN CORPORATION (KR) 2003-04-08 — — US disclosed
EP-1131312-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION, LTD. (KR) 2001-09-12 — — EP disclosed
WO-2000029403-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2000-05-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246965-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE CNR1, CNR2, OPRK1 MAOA 220/4885DRD2 43/4885TSHR 402/4885
US-20070213358-A1 PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF PGA5, ATP6AP1, PPOX MAOA 1709/4885DRD2 1885/4885TSHR 2226/4885
US-20070249658-A1 Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof ATP6AP1, HPD, ATP6V1H MAOA 2805/4885DRD2 900/4885TSHR 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.