Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.58 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514361 | 0.86 | ALOX15 (0.50) | BMP1DPP4DPP8DPP9ALOX15 | |
| SCHEMBL1674759 | 0.86 | ALOX15 (0.53) | BMP1DPP4DPP8DPP9ALOX15 | |
| SCHEMBL5971672 | 0.86 | ALOX15 (0.53) | BMP1DPP4DPP8DPP9ALOX15 | |
| Acetic Acid SCHEMBL30311271 | 0.85 | DPP4 (0.51) | BMP1DPP4DPP8DPP9ALOX15 | |
| SCHEMBL29478400 | 0.84 | BACE1 (0.54) | BMP1DPP4DPP8DPP9ALOX15 | |
| SCHEMBL25551968 | 0.84 | BMP1 (0.59) | BMP1DPP4DPP8DPP9BLM | |
| SCHEMBL30656951 | 0.84 | BMP1 (0.50) | BMP1DPP4DPP8DPP9GNPAT | |
| SCHEMBL29421937 | 0.84 | PTGS1 (0.50) | BMP1DPP4DPP8DPP9ALOX15 | |
| SCHEMBL14669745 | 0.83 | BMP1 (0.57) | BMP1DPP4DPP8DPP9BLM | |
| SCHEMBL14669847 | 0.83 | BMP1 (0.57) | BMP1DPP4DPP8DPP9BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | ESRRB, ESR1, ESRRA | BMP1 373/4885DPP4 664/4885DPP8 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.