Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005624 | 0.96 | KCNH2 (0.50) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL12334022 | 0.87 | GRM5 (0.44) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL26259889 | 0.87 | PDGFRB (0.54) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL12334019 | 0.86 | GRM5 (0.43) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL12334020 | 0.81 | EGFR (0.45) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL20681655 | 0.80 | KCNH2 (0.44) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL4269716 | 0.80 | PDGFRB (0.54) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL2774016 | 0.80 | FFAR1 (0.60) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL15895661 | 0.80 | ALDH1A1 (0.49) | PDGFRBPDGFRAEGFRKCNH2GRM5 | |
| SCHEMBL4096903 | 0.79 | AAK1 (0.50) | PDGFRBPDGFRAEGFRAAK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069732-A | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2023-11-17 | — | — | CN | disclosed |