Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.46 |
| ▸ | MRE11 | P49959 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.45 |
| ▸ | PRKACA | P17612 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225217 | 1.00 | HDAC6 (0.49) | HDAC6ROCK1MRE11ABL1PARP1 | |
| SCHEMBL21225216 | 1.00 | HDAC6 (0.49) | HDAC6ROCK1MRE11ABL1PARP1 | |
| Hydrochloric Acid SCHEMBL30319901 | 0.99 | HDAC6 (0.48) | HDAC6ROCK1MRE11ABL1PARP1 | |
| Hydrochloric Acid SCHEMBL23851366 | 0.99 | HDAC6 (0.48) | HDAC6ROCK1MRE11ABL1PARP1 | |
| Hydrochloric Acid SCHEMBL23851364 | 0.99 | HDAC6 (0.48) | HDAC6ROCK1MRE11ABL1PARP1 | |
| SCHEMBL22290906 | 0.90 | WNT3A (0.52) | HDAC6ROCK1MRE11ABL1XIAP | |
| SCHEMBL22290903 | 0.90 | WNT3A (0.52) | HDAC6ROCK1MRE11ABL1XIAP | |
| SCHEMBL31173224 | 0.90 | WNT3A (0.52) | HDAC6ROCK1MRE11ABL1XIAP | |
| SCHEMBL24049451 | 0.88 | ABL1 (0.47) | ROCK1MRE11ABL1PARP1ROCK2 | |
| SCHEMBL23714619 | 0.88 | MRE11 (0.46) | ROCK1MRE11ABL1PARP1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677738-A | Compounds and uses thereof | 福宏治疗公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4522280-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118043053-A | Methods of treating cancer | 福宏治疗公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023220219-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |