Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658119 | 1.00 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL24675336 | 1.00 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL30719996 | 0.84 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL30729648 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL24640582 | 0.81 | HDAC6 (0.42) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL30658111 | 0.81 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL24675338 | 0.81 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL29088953 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL29841730 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL30658112 | 0.81 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083274-A | Fused ring heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-11-17 | — | — | CN | disclosed |