Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477321 | 1.00 | MEN1 (0.73) | MEN1KMT2AATMMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL5887775 | 0.98 | MEN1 (0.70) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL488808 | 0.98 | MEN1 (0.68) | MEN1KMT2AATMMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL6550173 | 0.95 | KMT2A (0.65) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL9819626 | 0.87 | MEN1 (0.52) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL8391173 | 0.87 | MEN1 (0.52) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL11118757 | 0.85 | MEN1 (1.00) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL10895166 | 0.82 | MEN1 (0.94) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL16625789 | 0.80 | MEN1 (0.90) | MEN1KMT2AATMMAPTHSD17B10 | |
| SCHEMBL64167 | 0.78 | ATM (0.95) | MEN1KMT2AATMMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267711-A1 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF | CYTRX CORPORATION (US) | 2010-10-21 | — | — | US | disclosed |
| US-7745465-B2 | Method of enhancing cellular production of molecular chaperone, hydroxylamine derivatives useful for enhancing the chaperone production and the preparation thereof | CYTRX CORPORATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7148239-B2 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | CYTRX CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |
| CN-1152871-C | Hydroxylamine derivatives for enhancing the production of molecular chaperones and preparation thereof | �ݰ��п�˹�о���չ��˾ | 2004-06-09 | — | — | CN | disclosed |
| US-20040067940-A1 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | BIOREX RESEARCH & DEVELOPMENT CO. | 2004-04-08 | — | — | US | disclosed |
| US-20040019103-A1 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | BIOREX RESEARCH & DEVELOPMENT CO. | 2004-01-29 | — | — | US | disclosed |
| US-6653326-B1 | For example, N-(2-hydroxy-3-(1-piperidinyl)propoxy)-3-pyridinecarboximidoyl chloride maleate; inducing gene expression of an eukaryotic cell under physiological stress; antiallergens; autoimmune diseases; cardiovascular disorders | BIOREX RESEARCH & DEVELOPMENT CO. (HU) | 2003-11-25 | — | — | US | disclosed |
| EP-0801649-B1 | HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-08-07 | — | — | EP | disclosed |
| EP-0832079-B1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-03-27 | — | — | EP | disclosed |
| US-6180787-B1 | Process for preparing o-(3-amino-2-hydroxy-propyl)-hydroxymic acid halides | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 2001-01-30 | — | — | US | disclosed |
| US-5296606-A | O-(3-amino-2-hydroxypropyl)-hydroximic acid halides and process for preparing the same | BIOREX KUTATO-FEJLESZTO KFT (HU) | 1994-03-22 | — | — | US | disclosed |
| EP-0417210-B1 | NOVEL O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATO FEJLESZTOE KFT (HU) | 1994-03-09 | — | — | EP | disclosed |
| US-5218117-A | Antiallergens, antiinflammatory agents | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-06-08 | — | — | US | disclosed |
| US-5179089-A | Antiallergens, asthma | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-01-12 | — | — | US | disclosed |
| US-5147879-A | O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATO-FEJLESZTO KFT (HU) | 1992-09-15 | — | — | US | disclosed |
| EP-0486211-A1 | Isoquinoline derivatives | CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-20 | — | — | EP | disclosed |
| EP-0417210-A1 | NOVEL O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME. | BIOREX KUTATO FEJLESZTOE KFT (HU) | 1991-03-20 | — | — | EP | disclosed |
| WO-1990004584-A1 | NOVEL O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATÓ FEJLESZTO^' KFT. (HU) | 1990-05-03 | — | — | WO | disclosed |
| US-4308399-A | O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-12-29 | — | — | US | disclosed |
| US-4187220-A | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267711-A1 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF | HSPE1, HSF1, HSP90AB2P | MEN1 4335/4885KMT2A 3924/4885ATM 3403/4885 |
| US-20040019103-A1 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | HSPE1, HSF1, HSPA1A | MEN1 4141/4885KMT2A 3889/4885ATM 3134/4885 |
| US-20040067940-A1 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | HSPE1, HSF1, HSPA1A | MEN1 4141/4885KMT2A 3889/4885ATM 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.