Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 3/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.47 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401256 | 0.89 | ACACB (0.61) | ACACBITGB3ITGA2BCPA1ACE2 | |
| SCHEMBL29398348 | 0.89 | ACACB (0.61) | ACACBITGB3ITGA2BCPA1ACE2 | |
| SCHEMBL29666997 | 0.85 | LTA4H (0.54) | CTSLCTSKACACBFOLH1MME | |
| SCHEMBL30423308 | 0.83 | FOLH1 (0.71) | FOLH1CPA1ACE2MMEACE | |
| SCHEMBL8258366 | 0.83 | FOLH1 (0.50) | CTSLCTSKACACBITGB3ITGA2B | |
| SCHEMBL22498360 | 0.83 | FOLH1 (0.71) | FOLH1CPA1ACE2MMEACE | |
| SCHEMBL30845367 | 0.83 | FOLH1 (0.71) | FOLH1CPA1ACE2MMEACE | |
| SCHEMBL5869302 | 0.83 | FOLH1 (0.50) | CTSLCTSKACACBITGB3ITGA2B | |
| SCHEMBL30777486 | 0.83 | MME (0.65) | CPA1ACE2MMEACECPB1 | |
| SCHEMBL15692334 | 0.83 | MME (0.65) | CPA1ACE2MMEACECPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3954697-B1 | FLUORESCENT PROBE FOR DETECTING CALPAIN ACTIVITY | UNIV TOKYO (JP) | 2024-01-03 | — | — | EP | disclosed |