SCHEMBL29401256

SCHEMBL29401256

CC(=O)N[C@@H](Cc1ccc(OC(C)(C)C)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 4/20 0.61
▸ ITGB3 P05106 3/20 0.60
▸ ITGA2B P08514 3/20 0.60
▸ LMNA P02545 1/20 0.53
▸ FPR2 P25090 2/20 0.49
▸ ACE P12821 4/20 0.49
▸ MME P08473 3/20 0.49
▸ ACE2 Q9BYF1 3/20 0.49
▸ PPARG P37231 3/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ KDM4A O75164 1/20 0.47
▸ ABCB1 P08183 1/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ CPA1 P15085 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398348 1.00 ACACB (0.61) ACACBITGB3ITGA2BLMNAFPR2
SCHEMBL14606874 0.90 ACACB (0.62) ACACBITGB3ITGA2BLMNAABCB1
SCHEMBL30658624 0.89 CTSL (0.55) ACACBITGB3ITGA2BACEMME
SCHEMBL6781722 0.87 FPR2 (0.64) ACACBITGB3ITGA2BLMNAFPR2
SCHEMBL4378290 0.87 FPR2 (0.64) ACACBITGB3ITGA2BLMNAFPR2
SCHEMBL27569374 0.87 ITGB3 (0.56) ACACBITGB3ITGA2BFPR2ACE
SCHEMBL27569376 0.87 ITGB3 (0.56) ACACBITGB3ITGA2BFPR2ACE
SCHEMBL5065823 0.86 ITGB3 (0.67) ITGB3ITGA2BACEPPARGABCB1
SCHEMBL1062486 0.86 ITGB3 (0.67) ITGB3ITGA2BACEPPARGABCB1
SCHEMBL1311509 0.86 ITGB3 (0.67) ITGB3ITGA2BACEPPARGABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805476-B Preparation method of cetyl ester 南京莱昂生物科技有限公司 2024-05-28 — — CN claimed
CN-112940074-B Synthesis method of N-acetyl-L-tyrosyl-L-arginine hexadecyl ester 山东大学 2022-09-30 — — CN claimed
CN-114805476-A Preparation method of cetyl ester 南京莱昂生物科技有限公司 2022-07-29 — — CN claimed
US-12590065-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS, INC. (US) 2026-03-31 — — US disclosed
US-20240317688-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ZEVRA THERAPEUTICS, INC. 2024-09-26 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-12012384-B2 Dextrorphan prodrugs and processes for making and using them ZEVRA THERAPEUTICS, INC. (US) 2024-06-18 — — US disclosed
CN-114805476-B Preparation method of cetyl ester 南京莱昂生物科技有限公司 2024-05-28 — — CN disclosed
CN-114805476-B Preparation method of cetyl ester 南京莱昂生物科技有限公司 2024-05-28 — — CN disclosed
CN-117903238-A Synthesis process of acetyl dipeptide-1 cetyl ester 山东济肽生物科技有限公司 2024-04-19 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
CN-112940074-B Synthesis method of N-acetyl-L-tyrosyl-L-arginine hexadecyl ester 山东大学 2022-09-30 — — CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-114805476-A Preparation method of cetyl ester 南京莱昂生物科技有限公司 2022-07-29 — — CN disclosed
CN-114805476-A Preparation method of cetyl ester 南京莱昂生物科技有限公司 2022-07-29 — — CN disclosed
US-20220089544-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2022-03-24 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012384-B2 Dextrorphan prodrugs and processes for making and using them OGFR, OPRM1, CYP4F3 ACACB 4302/4885ITGB3 1662/4885ITGA2B 3488/4885
US-12590065-B2 Levorphanol prodrugs and processes for making and using them SLC16A3, SLC16A8, SLC16A1 ACACB 524/4885ITGB3 2453/4885ITGA2B 4098/4885
US-20240317688-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OGFR ACACB 4568/4885ITGB3 1550/4885ITGA2B 3627/4885
US-20220089544-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OGFR, OPRM1, CYP4F3 ACACB 4302/4885ITGB3 1662/4885ITGA2B 3488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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