Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32681778 | 1.00 | KMT2A (0.36) | KMT2ACYP3A4CYP2C19ATMALDH1A1 | |
| SCHEMBL1680252 | 1.00 | KMT2A (0.36) | KMT2ACYP3A4CYP2C19ATMALDH1A1 | |
| SCHEMBL29731059 | 1.00 | KMT2A (0.36) | KMT2ACYP3A4CYP2C19ATMALDH1A1 | |
| SCHEMBL618635 | 0.84 | GABRA1 (0.41) | KMT2ACYP3A4CYP2C19NQO2FAAH | |
| SCHEMBL1302413 | 0.82 | NQO2 (0.36) | KMT2ACYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL23526103 | 0.81 | CYP1A2 (0.41) | CYP3A4ALDH1A1LMNACYP1A2 | |
| SCHEMBL30013986 | 0.81 | CYP1A2 (0.41) | CYP3A4ALDH1A1LMNACYP1A2 | |
| SCHEMBL23526102 | 0.81 | CYP1A2 (0.41) | CYP3A4ALDH1A1LMNACYP1A2 | |
| SCHEMBL3062204 | 0.80 | NQO2 (0.33) | KMT2ACYP3A4CYP2C19ALDH1A1ALOX15 | |
| SCHEMBL7786046 | 0.80 | AOC3 (0.36) | KMT2ACYP3A4CYP2C19ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671743-A | Preparation method of (S) -1- (3-bromo-2-methoxyphenyl) ethan-1-ol | 石家庄手性化学有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-112852769-B | Method for preparing (S) -1- (2-methoxy-3-bromophenyl) ethanol | 中国科学院天津工业生物技术研究所 | 2021-10-08 | — | — | CN | claimed |
| CN-118496280-A | Chiral PNN manganese complex, preparation method thereof, catalyst composition and application | 河北农业大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-114671743-A | Preparation method of (S) -1- (3-bromo-2-methoxyphenyl) ethan-1-ol | 石家庄手性化学有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114671743-A | Preparation method of (S) -1- (3-bromo-2-methoxyphenyl) ethan-1-ol | 石家庄手性化学有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114671743-A | Preparation method of (S) -1- (3-bromo-2-methoxyphenyl) ethan-1-ol | 石家庄手性化学有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-112852769-B | Method for preparing (S) -1- (2-methoxy-3-bromophenyl) ethanol | 中国科学院天津工业生物技术研究所 | 2021-10-08 | — | — | CN | disclosed |
| CN-112852769-B | Method for preparing (S) -1- (2-methoxy-3-bromophenyl) ethanol | 中国科学院天津工业生物技术研究所 | 2021-10-08 | — | — | CN | disclosed |
| CN-112852769-A | Method for preparing (S) -1- (2-methoxy-3-bromophenyl) ethanol | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112852769-A | Method for preparing (S) -1- (2-methoxy-3-bromophenyl) ethanol | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| US-8889722-B2 | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor | SHIONOGI & CO., LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-8530668-B2 | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor | SHIONOGI & CO., LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8530668-B2 | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor | SHIONOGI & CO., LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8530668-B2 | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor | SHIONOGI & CO., LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20130217885-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | SHIONOGI & CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130217885-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | SHIONOGI & CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20100267783-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | EDDINGPHARM (HONG KONG) COMPANY LIMITED (CN) | 2010-10-21 | — | — | US | disclosed |
| US-20100267783-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | EDDINGPHARM (HONG KONG) COMPANY LIMITED (CN) | 2010-10-21 | — | — | US | disclosed |
| EP-2184279-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF | Shionogi&Co., Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
| EP-2184279-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF | Shionogi&Co., Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267783-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | MPL, TEK, THPO | KMT2A 3667/4885CYP3A4 1592/4885CYP2C19 895/4885 |
| US-20130217885-A1 | PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY, AND INTERMEDIATE THEREFOR | MPL, TEK, THPO | KMT2A 3659/4885CYP3A4 1634/4885CYP2C19 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.