Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548772 | 0.84 | GABRA1 (0.50) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL3065896 | 0.84 | KMT2A (0.36) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL32681778 | 0.84 | KMT2A (0.36) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL29731059 | 0.84 | KMT2A (0.36) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL23526102 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4LMNA | |
| SCHEMBL23526103 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4LMNA | |
| SCHEMBL30013986 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4LMNA | |
| SCHEMBL1680252 | 0.84 | KMT2A (0.36) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL1302413 | 0.82 | NQO2 (0.36) | CYP3A4CA2NQO2MEN1CYP2C9 | |
| SCHEMBL364729 | 0.79 | ALDH1A1 (0.46) | CA1CA2TSHRNQO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248535-B | Sila 1, 3-diether compound, preparation method thereof, olefin polymerization catalyst and olefin polymerization method | 国家能源集团宁夏煤业有限责任公司 | 2022-07-26 | — | — | CN | claimed |
| CN-113248535-A | Sila 1, 3-diether compound, preparation method thereof, olefin polymerization catalyst and olefin polymerization method | 国家能源集团宁夏煤业有限责任公司 | 2021-08-13 | — | — | CN | claimed |
| CN-117049961-A | Yeast dehydrogenase inhibitor derivative and synthesis method thereof | 苏州君叶生物医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-11702418-B2 | SOS1 inhibitors | Mirati Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| CN-113214415-B | Composite external electron donor, olefin polymerization catalyst and application thereof, and polyolefin and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113248535-B | Sila 1, 3-diether compound, preparation method thereof, olefin polymerization catalyst and olefin polymerization method | 国家能源集团宁夏煤业有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113214416-B | Combined external electron donor, olefin polymerization catalyst and application thereof, and polyolefin and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113087826-B | External electron donor composition, olefin polymerization catalyst and application thereof, and polyolefin and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113248535-A | Sila 1, 3-diether compound, preparation method thereof, olefin polymerization catalyst and olefin polymerization method | 国家能源集团宁夏煤业有限责任公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-113214415-A | Composite external electron donor, olefin polymerization catalyst and application thereof, and polyolefin and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214416-A | Combined external electron donor, olefin polymerization catalyst and application thereof, and polyolefin and preparation method thereof | 国家能源集团宁夏煤业有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| US-20090326175-A1 | ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS | SK ENERGY CO., LTD. (KR) | 2009-12-31 | — | — | US | disclosed |
| US-7589042-B2 | Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins | SK CORPORATION (KR) | 2009-09-15 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| WO-2009031798-A2 | ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME | SK ENERGY CO., LTD. (KR) | 2009-03-12 | — | — | WO | disclosed |
| EP-1910427-A1 | ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS | SK Energy Co., Ltd. (KR) | 2008-04-16 | — | — | EP | disclosed |
| US-20070135297-A1 | ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS | SK CORPORATION (KR) | 2007-06-14 | — | — | US | disclosed |
| WO-2007040294-A1 | ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS | SK ENERGY CO., LTD. (KR) | 2007-04-12 | — | — | WO | disclosed |
| US-20070004586-A1 | Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins | SK CORPORATION (KR) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326175-A1 | ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS | ESR1, ERO1A, PPOX | GABRA1 2919/4885GABRG2 2198/4885GABRB3 2572/4885 |
| US-11702418-B2 | SOS1 inhibitors | SOS1, SOS2, SOST | GABRA1 3926/4885GABRG2 3990/4885GABRB3 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.