Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659432 | 1.00 | MAPT (0.46) | MAPTKDM4ETHRBGPR119ALOX5AP | |
| SCHEMBL31442861 | 1.00 | MAPT (0.46) | MAPTKDM4ETHRBGPR119ALOX5AP | |
| SCHEMBL26100307 | 0.87 | MAPK1 (0.50) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL30659439 | 0.85 | THRB (0.46) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL30659271 | 0.82 | THRB (0.47) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL30659256 | 0.80 | MAPK1 (0.48) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL30659344 | 0.79 | KDM4E (0.49) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL20438981 | 0.79 | GPR119 (0.51) | MAPTKDM4ETHRBGPR119ALOX5AP | |
| SCHEMBL30844002 | 0.77 | SMN1; SMN2 (0.51) | MAPTKDM4ETHRBGPR119MAPK1 | |
| SCHEMBL31342284 | 0.77 | STS (0.51) | MAPTKDM4ETHRBGPR119ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536656-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239750-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |