Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816886 | 0.89 | PPARG (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28816885 | 0.89 | PPARG (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6706139 | 0.87 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1C4ALDH1A1AKR1B10 | |
| SCHEMBL6706138 | 0.87 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1C4ALDH1A1AKR1B10 | |
| SCHEMBL21457504 | 0.83 | MAPT (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21457502 | 0.83 | MAPT (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28110416 | 0.82 | MAOB (0.81) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13203402 | 0.82 | MAOB (0.81) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28068831 | 0.81 | MAOB (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28068830 | 0.81 | MAOB (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12102653-B2 | Ligand regulated protein-protein interaction system | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2024-10-01 | — | — | US | disclosed |
| US-20240000841-A1 | LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM | ST ANNA KINDERKREBSFORSCHUNG (AT) | 2024-01-04 | — | — | US | disclosed |