Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816885 | 1.00 | PPARG (0.50) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL30659497 | 0.89 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25210666 | 0.80 | MAPT (0.59) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL25210667 | 0.80 | MAPT (0.59) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL31233191 | 0.80 | MAPT (0.59) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL25207050 | 0.79 | MAOB (0.58) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL30382112 | 0.79 | MAOB (0.58) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL25207048 | 0.79 | MAOB (0.58) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL30739304 | 0.78 | MAPT (0.45) | PPARGPPARABCHEMAOBMGAM | |
| SCHEMBL27963663 | 0.78 | MAPT (0.45) | PPARGPPARABCHEMAOBMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104288133-B | 3,5-diisoamyl thiazolinyl, 2,4, the purposes of 4 '-trihydroxy chalcone and derivant thereof and preparation | TIANJIN UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104288133-A | 3,5-diisoamylene, 2,4,4'-trihydroxyl chalcone as well as use and preparation method of derivative of the 3,5-diisoamylene, 2,4,4'-trihydroxyl chalcone | UNIV TIANJIN SCIENCE & TECH | 2015-01-21 | — | — | CN | disclosed |