Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278404 | 1.00 | L3MBTL1 (0.49) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278556 | 0.86 | RORC (0.46) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278612 | 0.84 | RORC (0.44) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278560 | 0.84 | RORC (0.44) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278511 | 0.84 | HPGD (0.49) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278716 | 0.83 | RORC (0.46) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278383 | 0.83 | RORC (0.46) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278490 | 0.83 | RORC (0.47) | L3MBTL1RORCCYP11B1CYP11B2HTT | |
| SCHEMBL22278544 | 0.81 | RORC (0.44) | RORC | |
| SCHEMBL30660951 | 0.81 | RORC (0.44) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112839931-B | 1,2,3, 4-tetrahydroquinoxaline derivative, and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |