SCHEMBL30661237

SCHEMBL30661237

Cc1ccc(CN(C(=O)c2ccccc2Cl)c2ccc(F)c([Ti]c3c(F)ccc(N(Cc4ccc(C)cc4)C(=O)c4ccccc4Cl)c3F)c2F)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
RAB9A P51151 1/20 0.41
TP53 P04637 4/20 0.40
MAPT P10636 2/20 0.38
PDK1 Q15118 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
HSP90AA1 P07900 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27497666 0.86 POLB (0.45) POLBRAB9ATP53MAPTPDK1
SCHEMBL19970863 0.80 POLB (0.40) POLBRAB9ATP53MAPTPDK1
SCHEMBL27497665 0.77 POLB (0.47) POLBRAB9ATP53MAPTPDK1
SCHEMBL31385563 0.74 RIPK1 (0.41) CNR1CNR2
SCHEMBL27517544 0.69 CNR2 (0.44) POLBRAB9ATP53MAPTPDK1
SCHEMBL19970891 0.65 PDK1 (0.39) POLBRAB9ATP53MAPTPDK1
SCHEMBL27565956 0.65 TP53 (0.44) POLBRAB9ATP53MAPTLMNA
SCHEMBL4237595 0.62 CNR2 (0.58) RAB9ACNR2GAAHTT
SCHEMBL19868597 0.62 MEN1 (0.46) RAB9ACNR2GAAHTT
SCHEMBL27517543 0.62 CNR2 (0.46) POLBRAB9ATP53MAPTPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113383273-B Photosensitive resin composition, pattern forming method, cured film, laminate, and device 富士胶片株式会社 2023-11-14 CN disclosed