Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061099 | 0.99 | AOC3 (0.55) | AOC3MAPTPARP1CACNA1HSMO | |
| SCHEMBL3064209 | 0.87 | AOC3 (0.45) | AOC3MAPTPARP1SMOALDH1A1 | |
| SCHEMBL3058291 | 0.82 | HTT (0.46) | AOC3ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3060073 | 0.80 | PARP1 (0.51) | AOC3MAPTPARP1SMOALDH1A1 | |
| SCHEMBL27308006 | 0.79 | AOC3 (0.51) | AOC3CACNA1HSMOCACNA1GCACNA1I | |
| SCHEMBL2139557 | 0.78 | ALDH1A1 (0.54) | AOC3MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21921161 | 0.77 | AOC3 (0.50) | AOC3MAPTCACNA1HSMOALDH1A1 | |
| SCHEMBL2137278 | 0.77 | ALDH1A1 (0.55) | MAPTALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL8429477 | 0.77 | CYP1A2 (0.54) | AOC3MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL13445134 | 0.77 | SMO (0.82) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | AOC3 4426/4885MAPT 1379/4885PARP1 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.