Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060073 | 0.90 | PARP1 (0.51) | AOC3CXCR3ALDH1A1KDM4ETDP1 | |
| SCHEMBL3061099 | 0.88 | AOC3 (0.55) | AOC3ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3066232 | 0.87 | AOC3 (0.56) | AOC3ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2826534 | 0.83 | HRH3 (0.46) | AOC3CXCR3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12127778 | 0.81 | L3MBTL3 (0.47) | HRH3L3MBTL3 | |
| SCHEMBL12942919 | 0.80 | L3MBTL3 (0.46) | AOC3HRH3L3MBTL3 | |
| SCHEMBL2827886 | 0.78 | HRH3 (0.53) | AOC3CXCR3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2827541 | 0.77 | CXCR3 (0.53) | AOC3CXCR3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12367598 | 0.76 | HTT (0.48) | CXCR3ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2831874 | 0.74 | KDM4E (0.41) | CXCR3KDM4EPARP1HRH3SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | AOC3 4426/4885CXCR3 3555/4885ALDH1A1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.