Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664596 | 1.00 | KDM4E (0.50) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL26655902 | 1.00 | KDM4E (0.50) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL26655888 | 0.85 | KDM4E (0.54) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL6663891 | 0.81 | NCF1 (0.51) | SMN1; SMN2POLBL3MBTL1ADRA2CKMT2A | |
| SCHEMBL26655887 | 0.80 | ALDH1A1 (0.55) | KDM4EALDH1A1POLBWDR5KMT2A | |
| SCHEMBL30879098 | 0.80 | MAPT (0.61) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL12006141 | 0.80 | MAPT (0.61) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL13215402 | 0.80 | KDM4E (0.48) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL22450644 | 0.79 | MAPT (0.56) | KDM4EMAPTRAD52ALDH1A1HSD17B10 | |
| SCHEMBL189132 | 0.79 | MAPT (0.59) | KDM4EMAPTRAD52ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526307-A1 | PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF | Soltego, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225097-A1 | PYRIMIDOPYRIMIDONE COMPOUNDS AND METHODS OF USE THEREOF | SOLTEGO, INC. (US) | 2023-11-23 | — | — | WO | disclosed |